[5] As a proteolytic enzyme, serrapeptase helps break down proteins into amino acids. Serrapeptase is also anti-edemic, so it is used to prevent swelling and fluid retention. Theyre used to the instant fix of antibiotics. My team and I work to prevent heart attack, stroke, cancer, and dementia. In rare cases, serrapeptase may cause Stevens-Johnson syndrome, a severe skin reaction characterized by large blisters and even shedding skin. Hello, I was just wondering how you got on in the end with Serrapeptase and the shrinking of the chocolate cysts? Serrapeptase does not work; Serrapeptase has not been proven to be helpful; Serrapeptase has not been proven harmful; Serrapeptase seems to be safe when taken in moderation; So.serrapeptase is not harmful and could possibly work but most likely serrapeptase does not work to prevent scar tissue. Serrapeptase is widely found in supplement form. There were no side effects with nattokinase in multiple clinical trials. You can register a callback at http://www.mygoodhealthclub.com BMC Oral Health. These diseases could actually beprevented by eliminating inflammation in the early stages. I started using this in the hopes it would heal my total knee replacement scar surgery that is keeping my knees stiff. 10 Things You Always Wanted To Know About Serrapeptase. The treatment potential Pulmonary fibrosis is a scarring of the lungs that prevents oxygen moving around the body. Get the details about serrapeptase, why scientists are calling for more research and what you should know before you try it. Asian J Pharma Sci. I suggested he take Serrapeptase and he agreed to give it a try. Capsules appear to be the most popular form of serrapeptase supplements. If you need ongoing support then regular health coaching is available by registering at http://www.mygoodhealthclub.com Dr Simon Norton described the benefits as such, It greatly improved the quality of many of my patients lives. To view profiles and participate in discussions please. If you need more direct guidance, please contact the health coaches at admin@mygoodhealthclub.com, Hello! x. I don't know if my cysts are getting smaller but I don't have painful periods since I started taking it. You can add in serrapeptase to further help clear the arteries, or better still use the Blockbuster Allclear formula from Good Health Naturally for this purpose. When a bone or a joint or a ligament or a muscle is injured, the body builds a protective wall of fibrin around the wound. Supplements can interact with other supplements, nutrients, or medications. I happened to discover on my own that my carotid artery was so blocked from a random ultrasound what a shock that was. My plan is to take the 250,000 size 3X per day. Spencer Brooks is a science writer with a background in psychopharmacology and nutrition. Thank you! Please also consult your healthcare provider regarding the proper dosage for your specific needs. They were both studied in rats with Alzheimer's. A study in zebrafish suggested that serrapeptase might break down amyloid plaques better than nattokinase, but clinical trials comparing these two enzymes are completely lacking [2, 6].Some researchers are investigating how combinations of . Researchers believe serrapeptase could reduce symptoms through its anti-inflammatory and mucolytic (mucous-reducing) properties. This is especially important in people who may be prone to allergic reactions as new forms of proteins are introduced into their diet. Required fields are marked *. The colleague who mentionedit had great success. If we digest dietary proteins, we would probably digest serrapeptase too. https://www.sciencedirect.com/science/article/pii/S209517791 https://pubmed.ncbi.nlm.nih.gov/29618875/, https://pubmed.ncbi.nlm.nih.gov/32104332/, https://pubmed.ncbi.nlm.nih.gov/28351512/, https://pubmed.ncbi.nlm.nih.gov/24799449/, https://pubmed.ncbi.nlm.nih.gov/23812278/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265778/. For me, serrapeptase sounds good. You may need to take it for several months/year or more for best results. In addition, there are thousands of testimonials like the ones above. By Spencer Brooks My name is Ford Brewer. I have used serrapeptase in the past and started taking 3 250000 iu per day, I have increased this to 4 tablets per day and noticed a huge improvement. The enzyme naturally possesses anti-inflammatory properties, which is why it has been investigated as an alternative to commonly used non-steroidal anti-inflammatory agents. There is limited research on the benefits of serrapeptase, but some complementary and alternative medicine (CAM) practitioners suggest it exerts anti-inflammatory effects that may reduce pain and swelling. Dosage: How Much Serrapeptase Should I Take? Additionally, it is the same reason why so many people have suffered the consequences of serious illnesses. The good news is that doctors in countries like Germany, Japan and Singapore routinely prescribe the enzyme. Hi Maria, yes the SerraEnzyme 80,000iu is the same as the Serrapet, so you are fine to use either. My gp recommended naproxen 3 times per day and paracetamol in between to manage the pain. Interestingly, serrapeptase has recently been recommended as a potential therapy for COVID-19 symptoms. [1] Also known as serratiopeptidase, this enzyme has been used in various medical specialties, from surgery and orthopedics to dentistry and otorhinolaryngology. Twice a day, gently massage this oil onto your abdomen. Serrapeptase, also known as serratiopeptidase, is produced naturally within the digestive tract of silkworms. Many clinical studies have used serrapeptase doses of 10 to 60 milligrams daily. On a milligram to milligram basis, the fibrinolytic strength of lumbrokinase is about 300-fold stronger . By Brittany Lubeck, RD This includes proteins that have built up in the body due to injury or illness. Q: Dear Robert, I have abdominal adhesions and a blocked fallopian tubes as a result of previous surgeries including c-sections. Serrapeptase dissolves non-living tissues such as fibrin, plaque, blood clots, cysts and inflammation in all forms without harming living tissue. Dr Norton also used the enzyme to heal himself and the members of his family, achieving excellent results. Recent studies have successfully used similar fibrinolytic enzymes produced by microorganisms in the treatment of blood clots, specifically in relation to dissolving fibrin, a common artery-blocking compound. Some have reported that the cyst has drained by this method but it didn't really work with me that way, reduced but then didn't cure. [2], Scientists and health care researchers are still learning about the anti-inflammatory, mucolytic, proteolytic and fibrinolytic properties of serrapeptase. Not afraid to address tough issues as they come up, or dig deeper to find someone's true feelings about a subject. Many enzymes naturally occur in your body, including digestive enzymes. Inflammation can also manifest in different ways. Six Simple Serrapeptase Myths Busting The Truth From Fiction! I have been taking serrapeptase 40,000iu about 8-capsules a day for 2weeks now and today i am experiencing some pains i hope this means it is working! Find out if N-Acetyl Cysteine (NAC) can help with post nasal drip & general sinus congestion and about supplements that may reduce cold symptoms. For decades, humans have used serrapeptase as an anti-inflammatory supplement. https://www.serrapeptase-info.co.uk/buy-serrapeptase/Information about Serrapeptase, which is known as the second gift from the Silkworm! Given the potential harms and uncertain benefits, it may be best that these groups avoid serrapeptase. For your privacy, only your first name (from your account) followed by a random number will appear with your comment. They can offer their professional opinion and expert medical advice about whether serrapeptase is right for youincluding potential serrapeptase dangers, such as negative interactions with other medications or supplements youre taking. Serrapeptase may also help with asthma, carpal tunnel syndrome, blood clots, and ear, nose, and throat disorders. According to one review, serrapeptase exerts effects similar to cyclooxygenase-1 (COX-1) and cyclooxygenase-1 (COX-2) inhibitor drugs like Aleve (naproxen) and Celebrex (celecoxib). E-15 thriving there. Serrapeptase is a super enzyme and has been used in general surgery, orthopedics, dentistry, and gynecology, among other practices and procedures. [7] Serratia bacteria are essential to the silkworms survival. 2020;11:122. The way serratiopeptidase works is preventing the body from excessive self-protection. Journal of International Medical Research: Evaluation of Serratia Peptidase in Acute or Chronic Inflammation of Otorhinolaryngology Pathology: A Multicentre, Double-Blind, Randomized Trial Versus Placebo. Kind Regards. Learn how to enable it. Other studies have shown that, when used together with antibiotics, serrapeptase can be very effective, especially against antibiotic-resistant bacteria. Most studies use 10mg of serrapeptase taken every eight hours. And, if I may ask, what dose (doses)? Any info will help. The original supplement form of serrapeptase was derived from Serratia E-15 protease, also known as Serratia peptidasean enzyme made by a bioactive group of bacteria that evolved from the process that allows a silkworm to become a moth. I am getting more headaches now, actually, but I get headaches a lot so it's hard to tell why. It is also claimed to have an effect against the build-up of cardiovascular (CV) plaque. CAM practitioners contend that it has medical properties and can be used to treat pain and inflammation. Fibrin is formed through the action of thrombin (an enzyme) on fibrinogen (a blood protein). Statements made on this website have not been evaluated by the U.S. Food and Drug Administration. Discard serrapeptase supplements once their expiration date has passed. What Are the Side Effects of Serrapeptase? It might be helping, although that could be just natural healing. Check Price at Amazon. Eventual doubts about serrapeptase's efficacy led its manufacturer to withdraw it from the market in 2011 voluntarily. Please help us, its really urgent T_T, Hi Luthfa, we would advise your friend to follow the cancer health plan, as closely as possible, to include a ketogenic diet, exercise, relaxation, and accupressure if they are able to. In the 1970s, serrapeptase was discovered in the digestive tract of Japanese silk worms and found to be produced by the non-pathogenic bacteria called Serratia sp. Before starting serrapeptase, let your healthcare provider know about any existing health issues. Regarding SerraEnzyme 80,000iu, they can take up to 3-4 x 3 times per day if needed and even consider the SerraEnzyme Maximum Strength 250,000iu at full dose for a short time 3 x 3, to help kick start the process. Most substances have some degree of toxicity. I had BOTH carotid arteries scrapped out. A review of in vitro and in vivo serrapeptase lab studies included research on the following: Although we can learn from lab studies, human trials are required to confirm these and other potential uses of serrapeptase. There are many conditions said to be positively affected by serrapeptase. Serrapeptase is so powerful is because it naturally heals the body. Better yet, there were no reports of side effects (like a stomach or gastrointestinal irritation) with serrapeptase. These core nutrients, combined together, can provide a super supplement that studies show targets dozens of health and age-related issues. Int J Surg. Hello everyone, 2013;11(3):209-217. doi:10.1016/j.ijsu.2013.01.010. I am scheduled for a Laparoscopy A question about serrapeptase and ovarian cysts (endometrioma). I prescribed Serrapeptase for those with varicose veins on their legs. I found that the pain in the areas it was in worst increased for couple of days before it got better now i dont get pain on that side at all and just mild on the other side and now my periods are nowhere near painful just uncomfortable. Posted 6/6/2013 1:35 PM (GMT -8) Serrapeptase is great stuff. Plus, score 20% off! Other supplements may work like serrapeptase as there are many that have the same or similar health claims. Serrapeptase and nattokinase are often used as biofilms disrupters to help clear persistent infections alongside anti-microbial herbs and nutrients. Purchase serrapeptase from an herbal store or online dealer. YouTube: How Much Serrapeptase Should I Take? Dr. Jinaan Jawad. Sources that sell supplements also claim huge promises with serrapeptase. Could Serrapeptase Help You To Look Younger Than Your Years? Silkworms use this enzyme to break down their cocoons at birth. Brittany Lubeck, RD, is a nutrition writer and registered dietitian with a master's degree in clinical nutrition. Proteolytic enzymes help break down proteins into amino acids. If you make a statement of fact, such as whether a type of treatment does or does not work, state your basis -- such as personal experience or a published study. Tiwari M. The role of serratiopeptidase in the resolution of inflammation. Your Good Health Coaching Team. Unfortunately, the review could not conclude the effects of serrapeptase on facial pain. If you are going to take it orally, it is important that it is enteric-coated in order to protect it from being destroyed and rendered ineffective by your stomach acid before it can reach the intestine.. Fibrin is formed through the action of thrombin (an enzyme) on fibrinogen (a blood protein). This article will explore the potential uses of serrapeptase. conditions said to be positively affected by serrapeptase. Hi, my close friend is suffering from high stadium of cervix cancer and now her lung is infected too. There are other procedures to shrink or get rid of fibroids, but it's been said, they often grow back. Use a piece of a clean t-shirt to strain out the flowers. When polymerized fibrin gets tangled with platelets, the combo forms a clot over a wounded site. BOTH ops went OK. Oxysorb works best as a sublingual. The recommended dose is usually about 6 40,000iu capsules/day for the first month and then down to 3/day for another 4 months. Physician heal thyself is a quote found in Luke 4:23. Green recommends patients use Viviscal consistently for at least six months, which means committing to three packages since Viviscal recommends taking one tablet twice a day. By clearing away the problem tissue, the body's own healing system is able to replace it with healthy tissue. WebMD does not provide medical advice, diagnosis or treatment. Everything from thinking to blinking, enzymes are involved. Look for a product that has 5 mg or 10 mg pills. Related: What Are Peptides? 5. Talk with your healthcare provider about the right supplement for you. Yes you can take both at the same time, and i often recommend people do. It is not recommended to take while pregnant or breastfeeding. The recommended dosage is 4 drops so some distilled water might have to be added to get a nebulizer to function. Clinical studies done in the 1960s began to show its effect in reducing inflammation.. Jadhav SB, Shah N, Rathi A, Rathi V, Rathi A. Serratiopeptase: insights into therapeutic applications. Is it safe to take 4 x 250000 iu, as its made such a difference Im reluctant to reduce it. Here is the structure of the serrapeptase molecule. Sign up for early access to sales, product launches, the latest Bulletproof news and more! Take the serrapeptase on an empty stomach with 8 oz. I keep getting uti issues should I go to a 80,000 dose or what. Recommended doses vary depending on the reason it is being taken. What Are Peptides? The same review looked at five studies on serrapeptase for facial pain, swelling, and trismus (or lockjaw) often associated with oral surgery. Hi,I have seen where they mix Nattokinase / Serrapeptase together. 2021;26(1):229. doi:10.3390/molecules26010229. Serrapeptase is a proteolytic enzyme meaning it can break down or dissolve blood clots, fibrin, or plaque, amazingly Serrapeptase has shown in a small number of studies to be able to do this without causing any harm to the arteries. But if all you do to correct a muscle injury or joint pain is to take serratiopeptidase, it probably won't be enough to bring you back to health. Sivaramakrishnan G, Sridharan K. Role of serratiopeptidase after surgical removal of impacted molar: a systematic review and meta-analysis. Keep it out of direct sunlight. However, you may experience side effects when taking it. Dose 1 time a day. I have been signed off work for the everyone :) Once this is eliminated, the body can naturally begin healing itself. Giacobbe J, Benoiton B, Zunszain P, Pariante CM, Borsini A. However, "antibiotic-associated diarrhea is also seen a lot in . Start off high on 2 capsules 3 x per day, then reduce down to 1 x 3 after a couple of months. Hi Robert, Serrapeptase is most commonly used to decrease inflammation, pain and swelling. Serrapeptase should be supplemented on an empty stomach, which is 30 minutes before a meal or two hours after a meal, three times a day. Proponents of CAM claim that serrapeptase can help treat a wide range of medical conditions, especially those that involve inflammation. 4. Join now to save favorites and get all member benefits, including over 1,300 reviews. The Top 10 Supplements That Everyone Should Take, Feeling The Effects Of Stress? J Maxillofac Oral Surg. Serrapeptase is so powerful is because it naturally heals the body. How to Store Serrapeptase Storing supplements properly can ensure their quality is maintained. So serrapeptase is an enzyme that can break down or dissolve other proteins. However, doses of up to 60 milligrams daily have been used safely in short-term studies. Cover immediately with duct tape. SERRAPEPTASE | how i knew it worked | NEW UPDATE Terralyn Christie 6.3K views 10 months ago The Miracle of Serrapeptase & Proteolytic Enzymes Revealed | The Cabral Concept #1775 Dr. Stephen. It is recommended that you take serrapeptase on an empty stomach and avoid eating food for at least 30 minutes after taking it. How can I tell if serrapeptase is working on my ovarian cyst (endometrioma or "chocolate cyst"). Have you had any success dissolving your chocolate cyst with other natural methods? Side effects may include: You should stop taking serrapeptase and talk with your healthcare provider if you experience side effects. Lindsay, Your Good Health Coaching Team. Many thanks. It is the responsibility of you and your healthcare providers to make all decisions regarding your health. 2005 - 2023 WebMD LLC. (Remember, in the hierarchy of good prices of evidence, RCTs are the best, as opposed to an expert opinion which is the lowest. Hi Carrye, Blockbuster Allclear is the recommended product to help clear the arteries, as part of our full plan which you can see here: https://goodhealthhelpdesk.com/index.php?/HelpDeskDirect/Knowledgebase/Article/View/1890/86/peripheral-arterial-disease-health-plan However, once they try and see for themselves the amazing results, they are quick to shout of its benefits. As a dietary supplement it has been touted as having anti-inflammatory and analgesic properties and promoted as an alternative to NSAIDS, like ibuprofen, in treating conditions such as sinusitis and joint pain. The best-known enzymes are found in the digestive system, and they help the body break down and assimilate the macronutrients found in the foods you eat. Many resources still share that serrapeptase come from silk worms. This is false, at least for serrapeptase products manufactured in the US. Tamimi Z, Al Habashneh R, Hamad I, Al-Ghazawi M, Roqa'a AA, Kharashgeh H. Efficacy of serratiopeptidase after impacted third molar surgery: a randomized controlled clinical trial. Any improvement? Other times, I mixed the serrapeptase with aloe vera gel and dabbed it on with a Q-tip. It is believed that serrapeptase could very well alleviate common upper respiratory tract symptoms, like inflammation and pain. However, even if supplements are third-party tested, that doesnt mean they are necessarily safe for all or effective in general. Serrapeptase is now available throughout the world in enteric coated tablets that allow the enzyme to travel safely through stomach acid to the intestine where it is dispersed in the circulatory system to tissues and cells. In addition, other potential health benefits include: Serrapeptase may have the ability to reduce pain. That means it breaks down certain proteins when it comes in contact with them. I also did some exercise and got monthly massages it helped me tremendously .I took a X-ray 6 months after taking nattokinase and it revealed the cyst was gone. 21 Easy Recipes to Fuel Your Keto Journey, https://www.bulletproof.com/supplements/aminos-enzymes/serrapeptase-benefits-dosage/, What Is Serrapeptase? For example, one double-blind, placebo-controlled study showed that subjects who had taken it reported a significant reduction in pain compared to those who took the placebo.. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. [6] However, others need to be taken as supplements, as the body does not produce them (or doesnt produce them in adequate quantities). Always consult a healthcare provider for medical advice. Your last name and email address will not be displayed. I had no discharge took a couple of months before improvement i take two before bed and one when i wake up. Molecules. Hi Tom, yes, thats a good plan, and add Vitamin D3, K2 and Magnesium in to your routine as well to help prevent calcium deposits. Biotin helps with the metabolism of fatty acids, glucose (blood sugar, in other words), and amino acids in your body, the NIH reports. Serranol This is a combination formula of 80,000IU Serrapeptase, Ecklonia Cava, CurcuminX4000 and Vitamin D3. 2021;12:603997. The use of enzymes therapeutically is not a new concept and has been widely accepted for its healing properties. It reduces swelling, greatly reduces (my) joint pain, lowers blood pressure and thins blood (which counters Lyme's ability to thicken it). One study even touts serrepeptases tremendous ability to reduce inflammation. I do a plant based diet now for around 3 yrs now and 2 yrs vegan. Please enter your username or email address. It will also look at dosage recommendations and side effects, precautions, and interactions of serrapeptase supplements. Can I take them together? Due to a lack of research, there are no guidelines for the appropriate use of serrapeptase. Serrapeptaseis made by bacteria found in the gut of silkworms. Continue on this dose until needed and then you can work down as improvements continue to be made. More high-quality research is certainly needed to determine the role of serrapeptase in oral surgery. As a result, painful symptoms manifest as the bodys warning sign that something isnt right. It does this without unwanted side effects commonly occurring from taking pharmaceutical drugs. I hope that helps If youd like to learn about the basics of heart attack & stroke prevention for free. Serrapeptase appears well tolerated, yet little is known about its long-term safety. It helps in providing fast relief from inflammation and the symptoms of pain that can result in various health conditions. In 2006 my friend Maggie, a certified herbalist, sent me an email about Serrapeptase. Hello Kind Regards, The Serrapeptase.info Team, Your email address will not be published. According to one review, serrapeptase is sometimes used for this purpose either alone or along with steroids or non-steroidal anti-inflammatory drugs (NSAIDs). They got bigger after having the covid vaccine. When possible, choose a supplement tested by a trusted third party, such as United States Pharmacopeia (USP), ConsumerLabs, or NSF. After it weaves a silk cocoon and begins transforming into a moth, the silkworm releases Serratia bacteria from its gut. Serra Enzyme 80,000IU Serrapeptase (90 Quad-Strength Tablets) by SerraEnzyme Write a review How customer reviews and ratings work Top positive review All positive reviews Angela It works miracles! There are no guidelines for the appropriate use of serrapeptase in any form. Find the best products with instant access to our latest tests & reviews of over 1,300 health products. Bulletproof is a food and beverage company, known for Bulletproof Coffee and products that fuel your mind and body. Or, if it is working and breaking down some cyst (and maybe also some other endometrial tissue), would the broken down products "wait" until my period to be discharged? This statement couldnt be truer in one doctors case. Instead, serrapeptase can be found as a supplement in various forms. Is that normal for bleeding and headaches? ", International Journal of Oral & Maxillofacial Surgery: Effect of the proteolytic enzyme serrapeptase on swelling, pain, and trismus after surgical extraction of mandibular third molars., International Journal of Surgery: Serratiopeptidase: A systematic review of the existing evidence., Journal of Internal Medicine: Biofilm infections, their resilience to therapy and innovative treatment strategies.. Here are a few potential serrapeptase benefits and caveats: The bottom line: More research needs to be conducted to help solidify the links between serrapeptase and its potential health benefits. If you make a positive or negative comment about a product, note whether or not you have a financial interest in the product or in a competing product. (you know you may not have one or two, you could actually have 20 or more). High emotional intelligence/empathy. (40) However, it still lacks clinical research supporting its use in thromboembolic conditions. J Clin Diagn Res. It also improved swelling, but not significantly. Products sold on this website are not intended to diagnose, treat, cure, or prevent any disease. I tell them theyll need two tubs of Serrapeptase before they see results, confirms Linda. It does this without unwanted side effects commonly occurring from taking pharmaceutical drugs. It leads to shortness of breath, aching muscles and joints, and severe fatigue.. Fibrin around an internal injury acts a little like a scab on a skin wound. Therefore, it is important to talk to your healthcare provider about any supplements you plan to take and check in about potential interactions with other supplements or medications. Our goal is to help you understand how to prevent major killers and disablers. Yet, more research is needed to support these health claims. While chronic respiratory diseases (CRDs) do not have a known cure, there are ways to alleviate the pain and complications of CRDs and improve the quality of life. Therefore, people taking these and other similar medications should avoid using serrapeptase. Research suggests that serrapeptase may interfere with certain medications. Most of them are driven by the process of, If you want to know more about the science of preventive medicine or you have questions about certain aspects of your health, check out our. That's so frustrating that you had specific pains making you think it was working, and then no effect on the cyst! It is a major component of blood clots. doi:10.7860/JCDR/2016/21388.8302. Then I read somewhere about Serrapeptase, took this twice a day on an empty tummy and within 4 days of taking it the cyst completely disappeared !! This is due to serrapeptase's potential disruption of normal blood clotting. Is it true that NAC can help clear nasal passages? I would like the your product for inflammation because I also have lupus. Statements made on this website have not been evaluated by the U.S. Food and Drug Administration. Thank you, {{form.email}}, for signing up. 2016;10(8):ZD31-2. This remarkable book also contains detailed plans for over 240 health conditions. Its also been proven (in vitro) to significantly disrupt biofilm and allow far better penetration of ABX. Its titled Serratiopeptidase: A systematic review of the existing evidence. Its a review of all articles in PubMed, Cochrane Library, MEDLINE, and other sources of clinical trials that were published between May 1, 2011, and July 15, 2012. How Does Serrapeptase Work? The healing happens when the inflammation is dissolved and dissipated from the body. A small clinical trial compared serrapeptase to a placebo for people who had recently had a molar removed. Serrapeptase limits the ability of biofilm to form. The following is a look at some of the more compelling pieces of evidence in support of serrapeptase use. Digestive enzymes, Hydochloric acid and/or ox bile - to assist digestion 2. How did it fare for you? Cookies collect information about your preferences and your devices and are used to make the site work as you expect it to, to understand how you interact with the site, and to show advertisements that are targeted to your interests. In this post, lets look at serrapeptase, how it works, and whether there is enough basis for its promises.. How Peptides Work for Fat-Burning and Recovery, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585045/, https://pubmed.ncbi.nlm.nih.gov/23380245/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624573/, https://pubmed.ncbi.nlm.nih.gov/32119368/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312459/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923703, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883229/. This can be increased to 4 x 3 for greater . Because serratiopeptidase is a particularly potent enzyme, sometimes you don't need the others. In addition, it also has MSM and trace minerals. Designed to dissolve inflammation and support the bodys natural healing process. www.consumerlab.com/answers/does-serrapeptase-work/serrapeptase/. (Source: Baumann U. Shen P, Lin W, Deng X, et al. Unless you are taking the enzyme to help with sluggish digestion, take it on an empty stomach with a little water. Plus you can download Robert Redferns ebook on Fertility, which has helped many women go on to have successful pregnancies and healthy babies: https://naturallyhealthynews.com/health-books/